E-ISSN 2548-0839
Volume : 6 Issue : 2 Year : 2024

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1.8
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Journal Citation Reports (Clarivate, 2023)(Dentistry, Oral Surgery & Medicine (Science))
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European Endodontic Journal Measurement of Copper Ion Extrusion from the Apex of Human Teeth with Single Canal Following Electrophoresis [Eur Endod J]
Eur Endod J. 2021; 6(2): 226-229 | DOI: 10.14744/eej.2020.61687

Measurement of Copper Ion Extrusion from the Apex of Human Teeth with Single Canal Following Electrophoresis

Mohsen Aminsobhani1, Behnam Bolhari2, Behnam Dorost2, Ali Eslambol Nassaj3, Ellahe Azizlou4
1Department of Endodontics, Dental School, Aja University of Medical Sciences, Tehran, Iran
2Department of Endodontics, Dental School, Tehran University of Medical Sciences, Tehran, Iran
3Department of Endodontics, Dental School, Kerman University of Medical Sciences, Kerman, Iran
4Department of Endodontics, Dental School, Iran University of Medical Sciences, Tehran, Iran

Objective: Preventing bacterial overgrowth is an essential component of successful root canal treatment. Increasing the penetration of antimicrobial substances into the canal through electrophoresis is one of the possible methods. This study aimed to measure the copper ions extruding from the root apex after using an electrophoresis device (Depotphorese®) in human teeth with single canals.
Methods: In this ex-vivo study, thirty extracted human teeth with single canals were randomly divided into 2 groups. Group 1 as root canal preparation (WP) and group 2 as control (without root canal preparation). Each sample was individually fixed by alginate in a 5 ml sterile Eppendorf tube (microcentrifuge tube), and the root end was in contact with the distilled water solution. Ions derived from calcium hydroxide plus cupper paste (Cupral®) which mobilized via a low current electric field (1.5 mA/min for10 min) by Depotphorese® device. The copper ions in water solution were measured by spectrophotometric and supernatant methods.
Results: Copper ions were extruded from the end of the apex in two groups. However, based on the results of the t-test; copper ion penetration was significantly lower in the control group compared to the WP group (P<0.05).
Conclusion: Electrophoresis increased copper extrusion from the apical foramen. Although the root canal preparation increases the copper ion output in an ex-vivo environment, the amount of copper extruded from the root apex end was lower than the toxic dose. It seems that electrophoresis of copper plus calcium hydroxide mixture in endodontic treatments can be a safe procedure. (EEJ-2020-06-150)

Keywords: Cupral, electrophoresis, preparation, root canal

Mohsen Aminsobhani, Behnam Bolhari, Behnam Dorost, Ali Eslambol Nassaj, Ellahe Azizlou. Measurement of Copper Ion Extrusion from the Apex of Human Teeth with Single Canal Following Electrophoresis. Eur Endod J. 2021; 6(2): 226-229

Corresponding Author: Ellahe Azizlou
Manuscript Language: English
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