Effectiveness of Lidocaine vs Lidocaine with Magnesium Sulphate During Inferior Alveolar Nerve Block in Patients with Symptomatic Irreversible Pulpitis: A Randomized Double Blinded Clinical Trial

OBJECTIVE: This study aimed to compare the effectiveness of lidocaine with Magnesium sulphate in patients undergoing Root Canal Treatment (RCT) following irreversible pulpitis.
METHODS: A total of 86 patients were randomized to receive 1.8 ml of 2% lidocaine replaced with 0.2ml of 10% Magnesium Sulphate with 1: 80,000 epinephrine (n=43) as Group I and 1.8ml of 2% lidocaine with 1: 80,000 epinephrine (n=43) as Group II. Pre-op Visual Analogue Scale (VAS) pain scores were recorded. Patients were instructed to report any peri-op pain felt during the access cavity preparation and when introducing the first patency file (#10 k) in the root canal and peri- op VAS recorded
RESULTS: The age mean ± SD were 30.3 ± 9.02 and 26.39 ± 7.72 for Group I and Group II respectively. The mean ± SD of peri-operative pain was found to be 0.16 ± 0.37 in Group I and 3.13 ± 0.77 in Group II. Group I was found to have a higher mean value than Group II which was statistically significant (p = 0.01).
CONCLUSION: Based on the results, the addition of 10% magnesium sulphate to 2% lidocaine increased the effectiveness of Inferior Alveolar Nerve Block (IANB) in patients with symptomatic irreversible pulpitis of mandibular molar teeth. (EEJ-2023-03-042)