E-ISSN 2548-0839
Volume : 9 Issue : 3 Year : 2024

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Journal Citation Reports (Clarivate, 2024)(Dentistry, Oral Surgery & Medicine (Science))
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Diclofenac Transdermal Patch versus Oral Diclofenac on Post Endodontic Pain and Quality of Life: A Randomised Clinical Trial [Eur Endod J]
Eur Endod J. 2024; 9(3): 203-209 | DOI: 10.14744/eej.2024.37233

Diclofenac Transdermal Patch versus Oral Diclofenac on Post Endodontic Pain and Quality of Life: A Randomised Clinical Trial

Kajal Modi, Sathish Sundar, Dinesh Kowsky, Velmurugan Natanasabapathy
Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Meenakshi Academy of Higher Education and Research (MAHER), Chennai, India

Objective: To compare the effect of pre-treatment transdermal and oral diclofenac on post-endodontic pain level and oral health-related quality of life (OHRQOL) in patients with symptomatic irreversible pulpitis with apical periodontitis in mandibular molars following single visit root canal treatment.
Methods: This parallel-arm, randomised, double-blinded clinical trial is reported according to the Consoli-dated Standards of Reporting Trials (CONSORT) 2020 guidelines. The protocol was approved by the Institu-tional Ethical Committee on 30th March 2021 (MADC/IEC-I/029/2021) and registered at the clinical trial reg-istry of India (CTRI/2021/12/038696). Adult patients fulfilling the eligibility criteria were randomised into two groups. Group DTP received a diclofenac transdermal patch 100 mg, and Group DOT received a diclofenac oral tablet 100 mg one hour before root canal treatment. Pain scores were checked at baseline, 2, 4, 6, 8, 24, 48, and 72 hours after the treatment. OHRQOL was assessed at baseline and one week after the treatment.
Results: Both groups were associated with a significantly lower incidence of post-operative pain and im-proved OHRQOL. At 2 hours, the pain level was significantly lower with an oral diclofenac tablet, and at 24 hours, the pain level was significantly lower with a diclofenac transdermal patch. Regarding OHRQOL, there was no significant difference between the two groups.
Conclusion: Within the limitations of this study, the diclofenac transdermal patch had lesser post-operative pain at 24 hours, whereas the oral diclofenac tablet had lesser pain at 2 hours.

Keywords: Diclofenac, oral health-related quality of life, post-endodontic pain, transdermal patch

Corresponding Author: Velmurugan Natanasabapathy
Manuscript Language: English
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