Eur Endod J. Ahead of Print: EEJ-26566 | DOI: 10.14744/eej.2025.26566

Anesthetic Efficacy, Injection Pain and Pulse-rate Effect of Needle-free Injection in Pulpal Anesthesia of Maxillary Premolars with Irreversible Pulpitis: Randomized Clinical Study

Hatice Saðlam¹, Ertuðrul Karataþ^2
1Department of Endodontics, Biruni University, Faculty of Dentistry, Istanbul, Türkiye
²Department of Endodontics, Atatürk University, Faculty of Dentistry, Erzurum, Türkiye

Aim: This study aims to compare the pain perception associated with the needle-free system (Comfort-In™) and the standardt needle injection method during root canal treatments in adults.
Materials and Methods: Forty-four vital upper premolar teeth of the patients that applied to university for treatment and needed endodontic treatment were included in the study. Patients were anesthetized with two different injection methods; needle-free injection and conventional dental injection. In both groups, oxygen saturation and pulse measurements of the patients were recorded at 30-second intervals for 2 minutes before anesthesia and 4 minutes after anesthesia. Pain during the injection and opening of the access cavity preparation was recorded according to VAS. The data were analyzed according to a statistical program.
Results: In the study, a significant difference was found between the groups in terms of pain during anesthesia administration and the access cavity preparation(p<0.001). There were no significant differences in terms of gender and age (p<0.001). There was no significant differen-ce between the groups in terms of oxygen saturation and pulse values before and after treat-ment(p<0.001).
Conclusion: Needle-free injection makes the treatment more comfortable for patients with in-jection fear and anxiety, making the procedure easier for the physician and the patient. (EEJ-2024-12-197)

Keywords: Comfort-in, dental anesthesia, endodontic treatment, intraoperative pain, irreversible pulpitis, needle-free injection

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