E-ISSN 2548-0839
Anesthetic Efficacy of Lidocaine/Ketorolac in Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Randomized Clinical Trial []
. 2020; 5(3): 186-190 | DOI: 10.14744/eej.2020.74946

Anesthetic Efficacy of Lidocaine/Ketorolac in Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Randomized Clinical Trial

Hessamoddin Faghihian1, Reyhaneh Faghihian2, Abbasali Khademi3, Vivek Aggarwal4
1Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
2Department of Pediatric Dentistry, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
3Department of Endodontics, Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
4Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India

Objective: The purpose of this randomized, double-blind study was to evaluate the anesthetic efficacy of lidocaine-ketorolac administration by Inferior Alveolar Nerve Block (IANB) in patients with irreversible pulpitis.
Methods: Eighty-eight adult patients received a combination of either one cartridge of “2% lidocaine with 1: 80.000 epinephrine” (Li) plus one cartridge of a mixture of 0.8 mL of the same solution and 1mL ketorolac tromethamine (KT)(30 mg/mL), or one cartridge of Li solution plus one cartridge of a mixture of the same solution and saline. Endodontic access was prepared after fifteen minutes. Anesthetic success was defined as no or mild pain [less than 54 mm on the Heft-Parker visual analog scale (HP-VAS)] during access cavity preparation and initial file insertion. Chi-square test was used for data analysis, and the level of significance was set at 0.05 (P=0.05).
Results: Results showed that the success rates were 34.1% and 27.3% for Li-KT and Li-Saline groups, respectively, with no significant difference between the two groups (P=0.48). However, significant decrease of baseline mean VAS pain score of the participants in both groups was found during access cavity preparation or initial file insertion (P<0.05).
Conclusion: Mixed Li-KT solution did not increase the success rate of IANB injection significantly. (EEJ-2019-09-097)

Keywords: Inferior alveolar nerve block, irreversible pulpitis, ketorolac, iidocaine

Hessamoddin Faghihian, Reyhaneh Faghihian, Abbasali Khademi, Vivek Aggarwal. Anesthetic Efficacy of Lidocaine/Ketorolac in Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Randomized Clinical Trial. . 2020; 5(3): 186-190

Corresponding Author: Abbasali Khademi
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