E-ISSN 2548-0839
Volume : 8 Issue : 4 Year : 2023

Metrics

1.8
2022 IMPACT FACTOR
1.6
5 year Impact Factor
0.00041
Eigenfactor
2.6
2022 CiteScore
90/157
Journal Citation Reports (Clarivate, 2023)(Dentistry, Oral Surgery & Medicine (Science))
SCImago Journal & Country Rank
Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block with Patients Having Symptomatic Irreversible Pulpitis: A Double-Blinded, Randomized Controlled Trial [Eur Endod J]
Eur Endod J. 2023; 8(4): 246-252 | DOI: 10.14744/eej.2023.42650

Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block with Patients Having Symptomatic Irreversible Pulpitis: A Double-Blinded, Randomized Controlled Trial

Maryam Riaz1, Farjad Zafar2, Zara Khalid3, Tipu Sultan4, Aisha Wali5, Talha Mufeed Siddiqui3
1Department of Oral Biology, Baqai Medical University Dental College, Karachi, Pakistan
2Department of Dental Implantology, Baqai Medical University Dental College, Karachi, Pakistan
3Department of Operative Dentistry and Endodontics, Baqai Medical University Dental College, Karachi, Pakistan
4Department of Periodontology, Baqai Medical University Dental College, Karachi, Pakistan
5Department of Research and Development, Baqai Medical University Dental College, Karachi, Pakistan

Objective: The objective of this study was to evaluate the effectiveness of preoperative analgesics on inferior alveolar nerve blocks (IANB) during root canal treatment in patients with symptomatic irreversible pulpitis of the mandibular molars.
Methods: This study was a randomized, double-blinded, superiority trial with a parallel study design. A total of 120 subjects with symptomatic irreversible pulpitis were randomly assigned to one of four groups: group A (con- trol, Vitamin E, Evion 400 mg), group B (Diclofenac sodium, Voltral SR100 100 mg), group C (Piroxicam, Feldene 20 mg), and group D (Tramadol, Tramal 50 mg). The patients recorded preoperative pain levels, and after admin- istration of local anaesthesia intraoperative pain levels using the Heft-Parker visual analogue scale before and after the oral administration of the analgesics. Statistical analysis was performed using the Kruskal-Wallis test.
Results: All the analgesic groups showed a significant effect on the efficacy of the inferior alveolar nerve block in contrast to the control group (p<0.05). However, no significant difference was found between the drug groups on the effectiveness of the inferior alveolar nerve block (p>0.05). No side effects were reported in the present study.
Conclusion: Preoperative analgesics significantly increase the effectiveness of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis. Therefore, preoperative analgesics should be considered to increase the effectiveness of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis on the mandibular molars. (EEJ-2023-02-033)

Keywords: Inferior alveolar nerve block, local anaesthesia, preoperative analgesics, symptomatic irreversible pulpitis

Maryam Riaz, Farjad Zafar, Zara Khalid, Tipu Sultan, Aisha Wali, Talha Mufeed Siddiqui. Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block with Patients Having Symptomatic Irreversible Pulpitis: A Double-Blinded, Randomized Controlled Trial. Eur Endod J. 2023; 8(4): 246-252

Corresponding Author: Farjad Zafar
Manuscript Language: English
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