Eur Endod J. 2024; 9(4): 365-373 | DOI: 10.14744/eej.2024.30075

Regenerative Treatment of Mature Teeth with Pulp Necrosis and Apical Periodontitis Using Biodentine Compared with MTA: Randomized Controlled Clinical Trial

Amatallah Hussein Al Rawhani, Salsabyl Mohamed Ibrahim, Fatma Mohamed Abu Naeem
Department of Endodontics, Faculty of Dentistry, Cairo University, Cairo, Egypt

Objective: The purpose of this randomized, controlled study was to evaluate the effectiveness of Biodentine compared with MTA used as a pulp space barrier in healing periapical lesions and regaining pulp sensitivity after regenerative treatment in mature single-canal permanent teeth with pulp necrosis and apical periodontitis.
Methods: The study involved 36 patients with mature teeth with necrotic pulp and apical periodontitis. The patient underwent a regenerative treatment that utilized the blood clot technique. Teeth were randomly allocated to either the intervention, Biodentine, group (n=18) or the control, MTA, group (n=18). The healing of periapical lesions and tooth sensibility were evaluated throughout follow-up visits for up to 18 months.
Results: The study analyzed 31 patients; two patients within the biodentine group and three in the MTA group were lost to follow-up. After 18 months, both groups showed effective healing of periradicular lesions; 21 out of 31 patients (67.7%) were healed, ten patients (32.3%) were healing, and no failure cases occurred. There were no significant differences between the groups (p=1.00). More than 70% patients (22 out of 31) regained teeth sensibility, and the groups had no statistically significant difference (p=0.703).
Conclusion: Regenerative treatment using blood clots with either MTA or Biodentine effectively resolved periapical lesions and regained the sensibility of mature teeth. (EEJ-2024-03-053)

Keywords: Biodentine, healing periapical lesions mature teeth, procedure, regaining sensibility, regenerative endodontic MTA

---

CITE