E-ISSN 2548-0839
Volume : 9 Issue : 2 Year : 2024

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1.8
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1.6
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Journal Citation Reports (Clarivate, 2023)(Dentistry, Oral Surgery & Medicine (Science))
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European Endodontic Journal Incorporating Antimicrobial Nanomaterial and its Effect on the Antimicrobial Activity, Flow and Radiopacity of Endodontic Sealers [Eur Endod J]
Eur Endod J. 2017; 2(1): 16 | DOI: 10.5152/eej.2017.16029

Incorporating Antimicrobial Nanomaterial and its Effect on the Antimicrobial Activity, Flow and Radiopacity of Endodontic Sealers

Ana Beatriz Vilela Teixeira1, Carla Larissa Vidal1, Denise Tornavoi De Castro1, Christiano De Oliveira- Santos2, Marco Antônio Schiavon3, Andréa Cândido Dos Reis1
1Department of Dental Materials and Prosthesis, University of São Paulo School of Dentistry of Ribeirão Preto, Ribeirão Preto, Brazil
2Department of Stomatology, Publich Health and Forensic Dentistry, University of São Paulo School of Dentistry of Ribeirão Preto, Ribeirão Preto, Brazil
3Department of Natural Sciences, Federal University of São João Del- Rei, São João Del-Rei, MG, Brazil

Objective: This preliminary study aimed to evaluate the antimicrobial activity, flow and radiopacity of end- odontic sealers with nanostructured silver vanadate decorated with silver nanoparticles (AgVO3).
Methods: The minimum inhibitory concentration (MIC) of AgVO3 was evaluated against Enterococcus faeca- lis, Pseudomonas aeruginosa and Escherichia coli. Specimens were prepared from the following endodontic sealers: AH Plus (DENTSPLY DeTrey GmbH, Konstanz, Germany), Sealapex (Sybron Endo, Orange, CA, USA), Sealer 26 (DENTSPLY, Petrópolis, Brazil) and Endofill (DENTSPLY, Petrópolis, Brazil), with concentrations of 0%, 2.5%, 5% and 10% of AgVO3. Agar diffusion was used to evaluate the materials after 48 hours and 7 days (n=6). Flow (n=6) and radiopacity (n=9) were evaluated. The data were analysed by analysis of variance (ANOVA) and the Tukey honestly significant difference (HSD) (α=0.05).
Results: The MIC of AgVO3 was 500 μg/mL for E. faecalis and 31.25 μg/mL for P. aeruginosa and E. coli. The AgVO3 did not influence the antimicrobial activity of AH Plus against E. faecalis (P>0.05) but did promote this activity for Sealapex (P<0.01). Moreover, this activity increased for Endofill from 2.5% and for Sealer 26 from 5% (P<0.05). Against P. aeruginosa, only AH Plus and Endofill 10% inhibited zone formation (P<0.01). The anti- microbial activity of Endofill increased from 2.5% against E. coli (P<0.01). Sealapex 5% and 10% (P<0.01), Seal- er 26 10% and AH Plus promoted antimicrobial activity against E. coli. An increase in the zone of inhibition occurred between 48 hours and 7 days in the Sealapex 10% and Endofill 5% groups against E. coli. The flow of AH Plus and Endofill decreased with the increase of AgVO3 (P<0.05), and the flow of Sealer 26 and Sealapex was not affected (P>0.05). The radiopacity of AH Plus increased with AgVO3 (P<0.05). Endofill 5% and 10% did not differ from the control Endofill (P>0.05). The incorporation of AgVO3 did not influence the radiopacity of Sealer 26 (P>0.05). The incorporation of 2.5% and 5% AgVO3 reduced the radiopacity of Sealapex (P<0.05). Conclusion: Adding AgVO3 may increase the antimicrobial effect of endodontic sealers without major changes in their physicochemical properties.

Keywords: Antimicrobial agents, endodontics, microbiology, nanotechnology, obturation, radiography dental digital.

Ana Beatriz Vilela Teixeira, Carla Larissa Vidal, Denise Tornavoi De Castro, Christiano De Oliveira- Santos, Marco Antônio Schiavon, Andréa Cândido Dos Reis. Incorporating Antimicrobial Nanomaterial and its Effect on the Antimicrobial Activity, Flow and Radiopacity of Endodontic Sealers. Eur Endod J. 2017; 2(1): 16

Corresponding Author: Andréa Cândido Dos Reis, Brazil
Manuscript Language: English
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